The Alkaline Diet: Is There Evidence That an Alkaline pH Diet Benefits Health

Gerry K. Schwalfenberg

Abstract

This review looks at the role of an alkaline diet in health. Pubmed was searched looking for articles on pH, potential renal acid loads, bone health, muscle, growth hormone, back pain, vitamin D and chemotherapy. Many books written in the lay literature on the alkaline diet were also reviewed and evaluated in light of the published medical literature. There may be some value in considering an alkaline diet in reducing morbidity and mortality from chronic diseases and further studies are warranted in this area of medicine.

1. Background

Life on earth depends on appropriate pH levels in and around living organisms and cells. Human life requires a tightly controlled pH level in the serum of about 7.4 (a slightly alkaline range of 7.35 to 7.45) to survive [1].

As a comparison, in the past 100 years with increasing industrialization, the pH of the ocean has dropped from 8.2 to 8.1 because of increasing CO2 deposition. This has a negative impact on life in the ocean [1, 2] and may lead to the collapse of the coral reefs [3]. Even the pH of the soil in which plants are grown can have considerable influence on the mineral content of the food we eat (as minerals are used as buffers to maintain pH). The ideal pH of soil for the best overall availability of essential nutrients is between 6 and 7. Acidic soils below pH of 6 may have reduced calcium and magnesium, and soil above pH 7 may result in chemically unavailable iron, manganese, copper and zinc. Adding dolomite and manure are ways of raising pH in an acid soil environment when the pH is below 6 [4].

When it comes to the pH and net acid load in the human diet, there has been considerable change from the hunter gather civilization to the present [5]. With the agricultural revolution (last 10,000 years) and even more recently with industrialization (last 200 years), there has been an decrease in potassium (K) compared to sodium (Na) and an increase in chloride compared to bicarbonate found in the diet [6]. The ratio of potassium to sodium has reversed, K/Na previously was 10 to 1 whereas the modern diet has a ratio of 1 to 3 [7]. It is generally accepted that agricultural humans today have a diet poor in magnesium and potassium as well as fiber and rich in saturated fat, simple sugars, sodium, and chloride as compared to the preagricultural period [6]. This results in a diet that may induce metabolic acidosis which is mismatched to the genetically determined nutritional requirements [8]. With aging, there is a gradual loss of renal acid-base regulatory function and a resultant increase in diet-induced metabolic acidosis while on the modern diet [9]. A low-carbohydrate high-protein diet with its increased acid load results in very little change in blood chemistry, and pH, but results in many changes in urinary chemistry. Urinary magnesium levels, urinary citrate and pH are decreased, urinary calcium, undissociated uric acid, and phosphate are increased. All of these result in an increased risk for kidney stones [10].

Much has been written in the lay literature as well as many online sites expounding on the benefits of the alkaline diet. This paper is an attempt to balance the evidence that is found in the scientific literature.

2. The Role of pH in Various Cells, Organs, and Membranes

The pH in our body may vary considerably from one area to another with the highest acidity in the stomach (pH of 1.35 to 3.5) to aid in digestion and protect against opportunistic microbial organisms. But even in the stomach, the layer just outside the epithelium is quite basic to prevent mucosal injury. It has been suggested that decreased gastric lining secretion of bicarbonates and a decrease in the alkaline/acid secretion in duodenal ulcer patients may play a significant role in duodenal ulcers [11]. The skin is quite acidic (pH 4–6.5) to provide an acid mantle as a protective barrier to the environment against microbial overgrowth. There is a gradient from the outer horny layer (pH 4) to the basal layer (pH 6.9) [12]. This is also seen in the vagina where a pH of less than 4.7 protects against microbial overgrowth [13].

The urine may have a variable pH from acid to alkaline depending on the need for balancing the internal environment. Acid excretion in the urine can be estimated by a formula described by Remer (sulfate + chloride + 1.8x phosphate + organic acids) minus (sodium + potassium + 2x calcium + 2x magnesium) mEq [14]. Foods can be categorized by the potential renal acid loads (PRALs) see Table 2. Fruits, vegetables, fruit juices, potatoes, and alkali-rich and low phosphorus beverages (red and white wine, mineral soda waters) having a negative acid load. Whereas, grain products, meats, dairy products, fish, and alkali poor and low phosphorus beverages (e.g., pale beers, cocoa) have relatively high acid loads [15]. Measurement of pH of the urine (reviewed in a recent study with two morning specimens done over a five-year span) did not predict bone fractures or loss of bone mineral density [16]. However, this may not be reflective of being on an alkaline or acid diet throughout this time. For more details, see Table 1.

Table 2

Table 2

Potential renal acid loads (PRALs) of selected foods [20].
Table 1

Table 1

Ph of selected fluids, organs, and membranes.

3. Chronic Acidosis and Bone Disease

Calcium in the form of phosphates and carbonates represents a large reservoir of base in our body. In response to an acid load such as the modern diet these salts are released into the systemic circulation to bring about pH homeostasis [7]. It has been estimated that the quantity of calcium lost in the urine with the modern diet over time could be as high as almost 480 gm over 20 years or almost half the skeletal mass of calcium [21]. However, urinary losses of calcium are not a direct measure of osteoporosis. There are many regulatory factors that may compensate for the urinary calcium loss. When the arterial pH is in the normal range, a mild reduction of plasma bicarbonate results in a negative calcium balance which could benefit from supplementing bicarbonate in the form of potassium bicarbonate [22]. It has been found that bicarbonate, which increases the alkali content of a diet, but not potassium may attenuate bone loss in healthy older adults [23]. The bone minerals that are wasted in the urine may not have complete compensation through intestinal absorption, which is thought to result in osteoporosis. However, adequate vitamin D with a 25(OH)D level of >80 nmol/L may allow for appropriate intestinal absorption of calcium and magnesium and phosphate when needed [24]. Sadly, most populations are generally deficient in vitamin D especially in northern climates [25]. In chronic renal failure, correction of metabolic acidosis with bicarbonate significantly improves parathyroid levels and levels of the active form of vitamin D 1,25(OH)2D3 [26]. Recently, a study has shown the importance of phosphate in Remer’s PRAL formula. According to the formula it would be expected that an increase in phosphate should result in an increase in urinary calcium loss and a negative calcium balance in bone [27]. It should be noted that supplementation with phosphate in patients with bed rest reduced urinary calcium excretion but did not prevent bone loss [28]. The most recent systematic review and meta-analysis has shown that calcium balance is maintained and improved with phosphate which is quite contrary to the acid-ash hypothesis [29]. As well a recent study looking at soda intake (which has a significant amount of phosphate) and osteoporosis in postmenopausal American first nations women did not find a correlation [30]. It is quite possible that the high acid content according to Remer’s classification needs to be looked at again in light of compensatory phosphate intake. There is online information promoting an alkaline diet for bone health as well as a number of books. However, a recent systematic review of the literature looking for evidence supporting the alkaline diet for bone health found no protective role of dietary acid load in osteoporosis [31].

Another element of the modern diet is the excess of sodium in the diet. There is evidence that in healthy humans the increased sodium in the diet can predict the degree of hyperchloremic metabolic acidosis when consuming a net acid producing diet [32]. As well, there is evidence that there are adverse effects of sodium chloride in the aging population. A high sodium diet will exacerbate disuse-induced bone and muscle loss during immobilization by increasing bone resorption and protein wasting [33]. Excess dietary sodium has been shown to result in hypertension and osteoporosis in women [34, 35]. As well, dietary potassium which is lacking in the modern diet would modulate pressor and hypercalciuric effects of excess of sodium chloride [36].

Excess dietary protein with high acid renal load may decrease bone density if not buffered by ingestion of supplements or foods that are alkali rich [37]. However, adequate protein is necessary for prevention of osteoporosis and sarcopenia; therefore, increasing the amount of fruit and vegetables may be necessary rather than reducing protein [38].

4. Alkaline Diets and Muscle

As we age, there is a loss of muscle mass, which may predispose to falls and fractures. A three-year study looking at a diet rich in potassium, such as fruits and vegetables, as well as a reduced acid load, resulted in preservation of muscle mass in older men and women [39]. Conditions such as chronic renal failure that result in chronic metabolic acidosis result in accelerated breakdown in skeletal muscle [40]. Correction of acidosis may preserve muscle mass in conditions where muscle wasting is common such as diabetic ketosis, trauma, sepsis, chronic obstructive lung disease, and renal failure [41]. In situations that result in acute acidosis, supplementing younger patients with sodium bicarbonate prior to exhaustive exercise resulted in significantly less acidosis in the blood than those that were not supplemented with sodium bicarbonate [42].

5. Alkaline Supplementation and Growth Hormone

It has long been known that severe forms of metabolic acidosis in children, such as renal tubular acidosis, are associated with low levels of growth hormone with resultant short stature. Correction of the acidosis with bicarbonate [7] or potassium citrate [43] increases growth hormone significantly and improved growth. The use of enough potassium bicarbonate in the diet to neutralize the daily net acid load in postmenopausal women resulted in a significant increase in growth hormone and resultant osteocalcin [44]. Improving growth hormone levels may improve quality of life, reduce cardiovascular risk factors, improve body composition, and even improve memory and cognition [45]. As well this results in a reduction of urinary calcium loss equivalent to 5% of bone calcium content over a period of 3 years [46].

6. Alkaline Diet and Back Pain

There is some evidence that chronic low back pain improves with the supplementation of alkaline minerals [47]. With supplementation there was a slight but significant increase in blood pH and intracellular magnesium. Ensuring that there is enough intracellular magnesium allows for the proper function of enzyme systems and also allows for activation of vitamin D [48]. This in turn has been shown to improve back pain [49].

7. Alkalinity and Chemotherapy

The effectiveness of chemotherapeutic agents is markedly influenced by pH. Numerous agents such as epirubicin and adriamycin require an alkaline media to be more effective. Others, such as cisplatin, mitomycin C, and thiotepa, are more cytotoxic in an acid media [50]. Cell death correlates with acidosis and intracellular pH shifts higher (more alkaline) after chemotherapy may reflect response to chemotherapy [51]. It has been suggested that inducing metabolic alkalosis may be useful in enhancing some treatment regimes by using sodium bicarbonate, carbicab, and furosemide [52]. Extracellular alkalinization by using bicarbonate may result in improvements in therapeutic effectiveness [53]. There is no scientific literature establishing the benefit of an alkaline diet for the prevention of cancer at this time.

8. Discussion

The human body has an amazing ability to maintain a steady pH in the blood with the main compensatory mechanisms being renal and respiratory. Many of the membranes in our body require an acid pH to protect us and to help us digest food. It has been suggested that an alkaline diet may prevent a number of diseases and result in significant health benefits. Looking at the above discussion on bone health alone, certain aspects have doubtful benefit. There does not seem to be enough evidence that milk or cheese may be as detrimental as Remer’s formula suggests since phosphate does benefit bone health and result in a positive calcium balance. However, another mechanism for the alkaline diet to benefit bone health may be the increase in growth hormone and resultant increase in osteocalcin. There is some evidence that the K/Na ratio does matter and that the significant amount of salt in our diet is detrimental. Even some governments are demanding that the food industry reduce the salt load in our diet. High-protein diets may also affect bone health but some protein is also needed for good bone health. Muscle wasting however seems to be reduced with an alkaline diet and back pain may benefit from this as well. An alkaline environment may improve the efficacy of some chemotherapy agents but not others.

9. Conclusion

Alkaline diets result in a more alkaline urine pH and may result in reduced calcium in the urine, however, as seen in some recent reports, this may not reflect total calcium balance because of other buffers such as phosphate. There is no substantial evidence that this improves bone health or protects from osteoporosis. However, alkaline diets may result in a number of health benefits as outlined below

  1. Increased fruits and vegetables in an alkaline diet would improve the K/Na ratio and may benefit bone health, reduce muscle wasting, as well as mitigate other chronic diseases such as hypertension and strokes.
  2. The resultant increase in growth hormone with an alkaline diet may improve many outcomes from cardiovascular health to memory and cognition.
  3. An increase in intracellular magnesium, which is required for the function of many enzyme systems, is another added benefit of the alkaline diet. Available magnesium, which is required to activate vitamin D, would result in numerous added benefits in the vitamin D apocrine/exocrine systems.
  4. Alkalinity may result in added benefit for some chemotherapeutic agents that require a higher pH.

From the evidence outlined above, it would be prudent to consider an alkaline diet to reduce morbidity and mortality of chronic disease that are plaguing our aging population. One of the first considerations in an alkaline diet, which includes more fruits and vegetables, is to know what type of soil they were grown in since this may significantly influence the mineral content. At this time, there are limited scientific studies in this area, and many more studies are indicated in regards to muscle effects, growth hormone, and interaction with vitamin D.

References

1. Waugh A, Grant A. Anatomy and Physiology in Health and Illness. 10th edition. Philadelphia, Pa, USA: Churchill Livingstone Elsevier; 2007.
2. University, Birmingham oAa. Oceans reveal further impacts of climate change. ScienceDaily, 2010.
3. Hoegh-Guldberg O, Mumby PJ, Hooten AJ, et al. Coral reefs under rapid climate change and ocean acidification. Science. 2007;318(5857):1737–1742. [PubMed]
4. Dam-ampai SO J, Nilnond C. Effect of cattle manure and dolomite on soil properties and plant growth in acid upland soils. Songklanakarin Journal of Science and Technologh. 2005;27(supplement 3):727–737.
5. Ströhle A, Hahn A, Sebastian A. Estimation of the diet-dependent net acid load in 229 worldwide historically studied hunter-gatherer societies. American Journal of Clinical Nutrition. 2010;91(2):406–412. [PubMed]
6. Sebastian A, Frassetto LA, Sellmeyer DE, Merriam RL, Morris RC., Jr. Estimation of the net acid load of the diet of ancestral preagricultural Homo sapiens and their hominid ancestors. American Journal of Clinical Nutrition. 2002;76(6):1308–1316. [PubMed]
7. Frassetto L, Morris, Jr. R.C. RC, Jr., Sellmeyer DE, Todd K, Sebastian A. Diet, evolution and aging—the pathophysiologic effects of the post-agricultural inversion of the potassium-to-sodium and base-to-chloride ratios in the human diet. European Journal of Nutrition. 2001;40(5):200–213. [PubMed]
8. Konner M, Boyd Eaton S. Paleolithic nutrition: twenty-five years later. Nutrition in Clinical Practice. 2010;25(6):594–602. [PubMed]
9. Lindeman RD, Goldman R. Anatomic and physiologic age changes in the kidney. Experimental Gerontology. 1986;21(4-5):379–406. [PubMed]
10. Reddy ST, Wang CY, Sakhaee K, Brinkley L, Pak CY. Effect of low-carbohydrate high-protein diets on acid-base balance, stone-forming propensity, and calcium metabolism. American Journal of Kidney Diseases. 2002;40(2):265–274. [PubMed]
11. Malov YS, Kulikov AN. Bicarbonate deficiency and duodenal ulcer. Terapevticheskii Arkhiv. 1998;70(2):28–32. [PubMed]
12. Ohman H, Vahlquist A. In vivo studies concerning a pH gradient in human stratum corneum and upper epidermis. Acta Dermato-Venereologica. 1994;74(5):375–379. [PubMed]
13. Ferris DG, Francis SL, Dickman ED, Miler-Miles K, Waller JL, McClendon N. Variability of vaginal pH determination by patients and clinicians. Journal of the American Board of Family Medicine. 2006;19(4):368–373. [PubMed]
14. Remer T, Manz F. Estimation of the renal net acid excretion by adults consuming diets containing variable amounts of protein. American Journal of Clinical Nutrition. 1994;59(6):1356–1361. [PubMed]
15. Remer T. Influence of diet on acid-base balance. Seminars in Dialysis. 2000;13(4):221–226. [PubMed]
16. Fenton TR, Eliasziw M, Tough SC, Lyon AW, Brown JP, Hanley DA. Low urine pH and acid excretion do not predict bone fractures or the loss of bone mineral density: a prospective cohort study. BMC Musculoskeletal Disorders. 2010;11, article 88
17. Boelsma E, van de Vijver LPL, Goldbohm RA, Klöpping-Ketelaars IAA, Hendriks HFJ, Roza L. Human skin condition and its associations with nutrient concentrations in serum and diet. American Journal of Clinical Nutrition. 2003;77(2):348–355. [PubMed]
18. Ince BA, Anderson EJ, Neer RM. Lowering dietary protein to U.S. recommended dietary allowance levels reduces urinary calcium excretion and bone resorption in young women. Journal of Clinical Endocrinology and Metabolism. 2004;89(8):3801–3807. [PubMed]
19. Boron WF. Regulation of intracellular pH. Advances in Physiology Education. 2004;28:160–179. [PubMed]
20. Remer T, Manz F. Potential renal acid load of foods and its influence on urine pH. Journal of the American Dietetic Association. 1995;95(7):791–797. [PubMed]
21. Fenton TR, Eliasziw M, Lyon AW, Tough SC, Hanley DA. Meta-analysis of the quantity of calcium excretion associated with the net acid excretion of the modern diet under the acid-ash diet hypothesis. American Journal of Clinical Nutrition. 2008;88(4):1159–1166. [PubMed]
22. Sebastian A, Morris RC., Jr. Improved mineral balance and skeletal metabolism in postmenopausal women treated with potassium bicarbonate. New England Journal of Medicine. 1994;331(4):p. 279.
23. Dawson-Hughes B, Harris SS, Palermo NJ, Castaneda-Sceppa C, Rasmussen HM, Dallal GE. Treatment with potassium bicarbonate lowers calcium excretion and bone resorption in older men and women. Journal of Clinical Endocrinology and Metabolism. 2009;94(1):96–102. [PMC free article] [PubMed]
24. Heaney RP, Dowell MS, Hale CA, Bendich A. Calcium absorption varies within the reference range for serum 25-hydroxyvitamin D. Journal of the American College of Nutrition. 2003;22(2):142–146. [PubMed]
25. Schwalfenberg GK, Genuis SJ, Hiltz MN. Addressing vitamin D deficiency in Canada: a public health innovation whose time has come. Public Health. 2010;124(6):350–359. [PubMed]
26. Lu KC, Lin SH, Yu FC, Chyr SH, Shieh SD. Influence of metabolic acidosis on serum 1,25(OH)2D3 levels in chronic renal failure. Mineral and Electrolyte Metabolism. 1995;21(6):398–402. [PubMed]
27. Fenton TR, Lyon AW, Eliasziw M, Tough SC, Hanley DA. Phosphate decreases urine calcium and increases calcium balance: a meta-analysis of the osteoporosis acid-ash diet hypothesis. Nutrition Journal. 2009;8, article 41
28. Hulley SB, Vogel JM, Donaldson CL, Bayers JH, Friedman RJ, Rosen SN. The effect of supplemental oral phosphate on the bone mineral changes during prolonged bed rest. Journal of Clinical Investigation. 1971;50(12):2506–2518. [PMC free article] [PubMed]
29. Fenton TR, Lyon AW, Eliasziw M, Tough SC, Hanley DA. Meta-analysis of the effect of the acid-ash hypothesis of osteoporosis on calcium balance. Journal of Bone and Mineral Research. 2009;24(11):1835–1840. [PubMed]
30. Supplee JD, Duncan GE, Bruemmer B, Goldberg J, Wen Y, Henderson JA. Soda intake and osteoporosis risk in postmenopausal American-Indian women. Public Health Nutrition. 2011:1–7. [PubMed]
31. Fenton TR, Tough SC, Lyon AW, Eliasziw M, Hanley DA. Causal assessment of dietary acid load and bone disease: a systematic review & meta-analysis applying Hill’s epidemiologic criteria for causality. Nutrition Journal. 2011;10(1, article 41)
32. Frassetto LA, Morris RC, Jr., Sebastian A. Dietary sodium chloride intake independently predicts the degree of hyperchloremic metabolic acidosis in healthy humans consuming a net acid-producing diet. American Journal of Physiology—Renal Physiology. 2007;293(2):F521–F525. [PubMed]
33. Frings-Meuthen P, Buehlmeier J, Baecker N, et al. High sodium chloride intake exacerbates immobilization-induced bone resorption and protein losses. Journal of Applied Physiology. 2011;111(2):537–542. [PubMed]
34. Cappuccio FP, Meilahn E, Zmuda JM, Cauley JA. High blood pressure and bone-mineral loss in elderly white women: a prospective study. Lancet. 1999;354(9183):971–975. [PubMed]
35. Devine A, Criddle RA, Dick IM, Kerr DA, Prince RL. A longitudinal study of the effect of sodium and calcium intakes on regional bone density in postmenopausal women. American Journal of Clinical Nutrition. 1995;62(4):740–745. [PubMed]
36. Morris RC, Jr., Schmidlin O, Frassetto LA, Sebastian A. Relationship and interaction between sodium and potassium. Journal of the American College of Nutrition. 2006;25(3):262S–270S. [PubMed]
37. Barzel US, Massey LK. Excess dietary protein may can adversely affect bone. Journal of Nutrition. 1998;128(6):1051–1053. [PubMed]
38. Heaney RP, Layman DK. Amount and type of protein influences bone health. American Journal of Clinical Nutrition. 2008;87(5):156S–157S.
39. Dawson-Hughes B, Harris SS, Ceglia L. Alkaline diets favor lean tissue mass in older adults. American Journal of Clinical Nutrition. 2008;87(3):662–665. [PMC free article] [PubMed]
40. Garibotto G, Russo R, Sofia A, et al. Muscle protein turnover in chronic renal failure patients with metabolic acidosis or normal acid-base balance. Mineral and Electrolyte Metabolism. 1996;22(1–3):58–61. [PubMed]
41. Caso G, Garlick PJ. Control of muscle protein kinetics by acid-base balance. Current Opinion in Clinical Nutrition and Metabolic Care. 2005;8(1):73–76. [PubMed]
42. Webster MJ, Webster MN, Crawford RE, Gladden LB. Effect of sodium bicarbonate ingestion on exhaustive resistance exercise performance. Medicine and Science in Sports and Exercise. 1993;25(8):960–965. [PubMed]
43. McSherry E, Morris RC., Jr. Attainment and maintenance of normal stature with alkali therapy in infants and children with classic renal tubular acidosis. Journal of Clinical Investigation. 1978;61(2):509–527. [PMC free article] [PubMed]
44. Frassetto L, Morris RC, Jr., Sebastian A. Potassium bicarbonate reduces urinary nitrogen excretion in postmenopausal women. Journal of Clinical Endocrinology and Metabolism. 1997;82(1):254–259. [PubMed]
45. Wass JAH, Reddy R. Growth hormone and memory. Journal of Endocrinology. 2010;207(2):125–126. [PubMed]
46. Frassetto L, Morris RC, Jr., Sebastian A. Long-term persistence of the urine calcium-lowering effect of potassium bicarbonate in postmenopausal women. Journal of Clinical Endocrinology and Metabolism. 2005;90(2):831–834. [PubMed]
47. Vormann J, Worlitschek M, Goedecke T, Silver B. Supplementation with alkaline minerals reduces symptoms in patients with chronic low back pain. Journal of Trace Elements in Medicine and Biology. 2001;15(2-3):179–183. [PubMed]
48. Zofková I, Kancheva RL. The relationship between magnesium and calciotropic hormones. Magnesium Research. 1995;8(1):77–84. [PubMed]
49. Schwalfenberg G. Improvement of chronic back pain or failed back surgery with vitamin D repletion: a case series. Journal of the American Board of Family Medicine. 2009;22(1):69–74. [PubMed]
50. Groos E, Walker L, Masters JR. Intravesical chemotherapy. Studies on the relationship between pH and cytotoxicity. Cancer. 1986;58(6):1199–1203. [PubMed]
51. Smith SR, Martin PA, Edwards RHT. Tumour pH and response to chemotherapy: an in vivo 31P magnetic resonance spectroscopy study in non-Hodgkin’s lymphoma. British Journal of Radiology. 1991;64(766):923–928. [PubMed]
52. Raghunand N, Gillies RJ. pH and chemotherapy. Novartis Foundation Symposium. 2001;240:199–211. [PubMed]
53. Raghunand N, He X, Van Sluis R, et al. Enhancement of chemotherapy by manipulation of tumour pH. British Journal of Cancer. 1999;80(7):1005–1011. [PMC free article] [PubMed]

Alimente care mentin arterele curate

Arterele se ocupa de transportarea oxigenului si a substantelor nutritive catre inima si creier. Aceste artere ar trebui sa fie puternice si flexibile, astfel incat sangele sa curga prin ele cu usurinta.  Totusi, pe masura ce imbatranesti, in interiorul arterelor se fac depozite de colesterol, deseuri celulare sau calciu. Toate aceste substante depuse pe peretii arterelor reduc viteza cu care sangele circula  sau ii potbloca acestuia accesul, provocand bolile cardiovasculare, accidente vasculare cerebrale sau chiar atacuri de cord.

Blocarea arterelor este asociata cu alimentatia nepotrivita. Mancarurile prelucrate, cele cu grasimi si multe chimicale duc in timp la blocarea arterelor provocand, pentru inceput, dificultati de respiratie sau dureri in piept.  Totusi, exista si o serie de alimente care curata foarte bine arterele si indeparteaza depozitele de grasime acumulate de-a lungul timpului.

Asadar, iata ce alimente ar trebui sa consumi mai des in acest sens:

Usturoi

Usturoiul este folosit din timpuri stravechi pentru tratarea bolilor de inima si hipertensiune, iar un studiu recent a demonstrat ca usturoiul poate inhiba calcifierea arterelor. Un alt studiu realizat de un medic german a aratat ca persoanele care consuma in mod frecvent pudra de usturoi  au arterele mai curate si sangele circula cu rapiditate, oferind inimii si creierului nutrientii necesari.

Struguri

Strugurii, mai exact flavonoidele din acestia sunt benefici in prevenirea formarii cheagurilor de sange si impiedica formarea depunerilor de grasime.  Consuma cel putin jumatate de kilogram de struguri saptamanal pentru a mentine arterele perfect curate.

Fructe de padure

Zmeura, afinele sau murele sunt si ele bogate in flavonoide, asemenea strugurilor, asa ca au acelasi efect de curatare a arterelor. Consuma-le ca atare sau in diverse prajituri, de preferat preparate in casa, cu o cantitate redusa de zahar.

Mere

Merele contin pectina, o substanta care are puterea de a scadea nivelul colesterolului din sange si, astfel, de a indeparta grasimile de pe peretii arterelor. Consuma merele ca atare sau sub forma de sub, ori ca si desert (mar cu biscuite si scortisoara).

Spanac

Spanacul are in compozitia sa luteina, o substanta care previne atacurile de cord prin mentinerea arterelor curate si prin impiedicarea acumularii de colesterol la nivelul vaselor de sange.


Alte alimente care mentin arterele curate sunt:

  • Carnea de peste (somon, ton etc)
  • Ulei de masline
  • Rosii
  • Ceai verde
  • Rodie.
sursa: sanatate.acasa.ro

What Is Food Intolerance and Why Is It So Important?

 Food Intolerance- Man and Animals versus Gluten, Casein, Soy, and Corn

 This critically important health issue of food intolerance is finally coming out of the closet and into its own. But what is it and why have we not heard of it before. The former is pretty easy to understand. Grasping the answer to the latter takes some serious effort and is not for the faint of heart.

 The term “food intolerance” has been applied to both immune-mediated (involving the immune system) and non-immune related disorders (eg to food additives) that result from the consumption of certain foods to which an individual is sensitive. Here is the Wikipedia definition of food intolerance: http://en.wikipedia.org/wiki/Food_intolerance . This is a pretty good starting point. But things are not always that clear-cut as we are finding in the study of celiac disease (gluten intolerance), the condition that catapulted me into this mission.

 This site focuses on the immune-mediated forms of food intolerance, which include those reactions to gluten, casein (dairy), soy, and corn. I also now have a small section on nightshade intolerance . In my GARD diet, I emphasize the need to eliminate MSG (monosodium glutamate) and aspartate (Nutrisweet), two food additives that are neurotoxic, with some individuals having much more dramatic reactions to their consumption than others. Some would call this a food intolerance. Like many other “intolerances”, these items affect everyone negatively to some extent but produce serious reactions in those who are already in a downward spiral from others factors.

The most serious food intolerances are those to the gluten grains (wheat, barley, and rye), casein (dairy products), soy and corn, with the first three being the most common. Celiac disease (gluten intolerance) is finally making its way into the public eye. At the time of my diagnosis in the year 2000, it was considered a “rare disorder in the US, affecting less than 1:5000 Americans.” In 2006, it was declared to be one of the most common conditions in the country, with Johns Hopkins and The Mayo Clinic stating that the official number of celiacs in this country was 1:120 people. However, the unofficial number by celiac researchers is a whopping 1:30. Other papers on this site address this obvious and unsettling discrepancy.

 Celiac disease, which serves very well as the example of the immune-related food intolerances, is caused by the reaction of the cells that line the intestinal tract to the presence of gluten, a sticky glycoprotein (part carb, part protein). This reaction to the lectins in gluten leads to the classic lesion of villous atrophy, the destruction of the tiny finger-like projections of the intestinal tract that are responsible for the absorption of nutrients. The main area of intestinal damage is the duodenum, that first stretch of intestine after the stomach. As the condition progresses, the next section- the jejunum- is also involved. This progression of villous damage along the length of the small intestine helps to explain the variability in symptoms among affected individuals, both in severity and age of onset.

 The destruction of the intestinal villi results in a number of serious complication, including the malabsorption of essential nutrients, the entry of undesirable proteins, and the leakage of certain important elements into that damaged gut. These things are often described as the “leaky gut syndrome”.

 The most important thing for the novice to grasp is the malabsorption issue. It is this part of the mechanism of food intolerance that helps people to see the potentially devastating aspects of this important health issue. The duodenum and jejunum are responsible for the absorption of the vast majority of our calcium, iron, iodine, B complex, C, and trace minerals (zinc, magnesium, boron, chromium, lithium, manganese, etc.). Immediately, one should be able to see the potentially catastrophic effects of damage to these areas: Osteoporosis, iron deficiency anemia, thyroid problems, immune system failure, and a myriad of symptoms related to trace element deficiencies. All tissues of the body can suffer from such malnutrition. So, we should not be surprised to learn that celiacs have a much higher rate of the illnesses that plague mankind…and his pets.

But gluten intolerance is only one of the “big 4” or what I like to refer as “the four horsemen of the apocalypse” when I am writing more melodramatically. I have good reason to do so. Gluten, dairy products, soy and corn are doing an incredible amount of harm to a phenomenal number of people and animals. We covered the incidence of celiac diseases above. What is the true incidence of casein, soy and corn intolerance? No one really knows for sure. But I can tell you that wheat is “only” the number two human food allergen, with cow’s milk being number one. That fact combined with the amount of research information linking dairy products to many of the common medical conditions from which we all suffer has led me to the conclusion that true dairy intolerance (to casein and other glycoproteins in cow’s milk) will be found to have a higher incidence in people than celiac disease.

 The bad news is that over 75% of the calories in the standard American diet (SAD) are derived from the “big 4”. Once we grasp the true incidence, the devastating consequences, and all of the common food sources of these food intolerances we will have a much better view of the big picture of medicine. The origins of the downward spiral in our health and that of our pets will be so clear that we should all wake up to what we have done to ourselves.

 And then we can embrace what I like to call the “gospel of medicine”: We do have our health destinies more in our own hands than we have ever believed, certainly more than we have ever been told. Miracles can occur when we identify and eliminate the foods that are driving our bodies (and the viruses they contain) crazy. I am a living example. Many others are experiencing profound results as seen in my testimonials section.

The rest of this Website is dedicated to helping the reader grasp the vital nature of this information as well as covering other topics that contribute to the decline in our health (eg air quality issues , sleep , and ” genetics “). When taken as whole, these issues should lead the reader to the same conclusion that I have came to a number of years ago: We are doing all of this harm to ourselves. That is an unsettling but true realization. But that same conclusion should give us hope for the future. This situation is still within our control. We can change things, in our household and beyond. It is not easy but it is “simple”. All we have to do is stop doing to ourselves what we know to be harmful and then reap the benefits. Yes, in our medical lives, we also reap what we sow.

 In a nutshell, after all of my research into so many of the medical problems and conditions that plague pets and mankind, I decided that the center of our health universe lies in the stretch of small intestine known as your duodenum and jejuneum, the first two segments of bowel after the stomach. Most celiacs are aware of the pathophysiology of their condition and are familiar with the terms malabsorption and “leaky gut syndrome”. But, many are like I was in that they don’t understand all of the fine details.

 There are four food ingredients that adhere to the villi of the small intestine and induce the change that is characteristic of celiac disease known as villous atrophy. These four substances are gluten (from the grains), casein (from cow milk products), soy protein, and corn gluten. Oh oh. Did you know that the last one was on the list? Hopefully so.

What is it that links these substances together? For one, they are all use as adhesives, either as non-food glues or as binders in the foods we consume. Gluten, casein, soy and even corn are all used in industry as adhesives, some even being waterproof. Put “gluten”, “casein”, “soy protein adhesive” or “corn adhesive” in the search engine of any computer and read the responses. Wow! They are not only used in the food industry to hold items such as oats together but they are put to use in industry to hold just about anything together.

 As we all know, it is the nature of the starches to be sticky. And, as it turns out, the

foods that are the “stickiest” are the ones that cause the most problems. This should not be a surprise once this issue is introduced. Casein and gluten are used for the most powerful adhesives. Therefore, it should be not be a shock that they are the number one and number two childhood food allergens according to the FDA. What is number four? Soy. What is number three? Eggs. (This is the first secondary allergen brought about by the damage done to the gut by the first two. Google “zonulin” for some interesting reading.)

 Now, imagine these proteins leaving the stomach of a human or their pet. I have always used the illustration of three slices of pizza leaving our stomach. But, for this sake of this article, I will use a wheat, barley, or soy-based pet food to drive the point home. Now that you have an idea of where we are headed, you can imagine the stomach is filled with “glue-containing” food. This “glue” leaves the stomach after it has been worked on as much as possible by that organ. Of course, not being a ruminant like a cow or sheep, these foods are not completely broken down any more than the cellulose that they eat that non-ruminants are unable to digest. As simple-stomached animals, our pets and we are not designed to eat grasses like the ruminants do and all of the grains are in the grass family. They are all grasses that man has chosen to consume, with those in Asia picking their grass (rice), the Europeans choosing their grasses (wheat and barley), and those in central America picking corn. Here in America, we consume them all and in abundance.

 In an attempt to digest these grasses and their “glue” (along with dairy and soy), our stomach adds as much acid as possible to break them down. Heart burn, anyone? (Yes, my two years of acid reflux abated after just one week of being gluten- free. This, again, should be no surprise.) But, the increased acid is inadequate to eliminate the “glue”. It is this sticky substance that adheres to the villi of the small intestine. Whether it be from wheat, cow milk, soy, corn, or the others mentioned, it adheres to these finger-like projections of the small intestine that are vital for the absorption of nutrients, effectively reducing the amount of those essential ingredients that would be absorbed into the bloodstream.

 What are those nutrients? The vital substances are calcium, iron, iodine, all B complex, vitamin C, most water-soluble vitamins, and most of our trace minerals such as zinc, boron, manganese, magnesium and more. In other words, just about everything that is important other than our fat soluble vitamins are absorbed by the duodenum and jejunum. How well can the small intestine function when it is coated with “glue”? The important thing to realize here is that this happens to some degree in everyone and every pet that eats these foods.

 That bears repeating: This happens some degree in everyone and every simple-stomached creature that eats these foods. We have simply focused on the worst-of-the-worst- as in the celiacs, casein intolerants, and soy intolerants- in which an immune response is mounted against the glue leading to severe villous atrophy. This immune assault also generates the warning antibodies that we call “allergies” to tell you that this is destructive process is taking place. Otherwise, it would be a “stealth operation” that goes on undetected for years and years until the bottom falls out. Yes, this is all too familiar of a scenario as well, isn’t it? It happens in pets all of the time, I’m afraid.

So, the ultimate question is whether pets suffer from celiac disease? My answer is that it doesn’t really matter whether we find that gluten intolerance affects all breeds of dogs and cats. In the pet, every bite of the average commercial food has “glue” in it, whether it is of wheat, barley, soy, corn, or rice origin. Yes, there are better glues” than others and they are in line with what we see as the principle allergens in the pet, just as one would expect. Wheat and soy are the worst (now that dairy has been eliminated from pet foods) while oats and rice are the best- the least sticky. Corn is in the middle.

 The veterinary profession was just as shortsighted as the medical profession is today about the ramifications of consuming the top food allergens as the bulk of the diet. 60-70% of the American diet is comprised of cow milk products and wheat alone, with 40-50% being the number one food allergen, dairy products. There is a price to pay for this sort of ignorance and it is heavier than most realize.

 The main cost is the disruption of small intestinal function. Once the essential nutrients have been malabsorbed for a long enough time, Pandora’s Box is opened. This may occur every early in life or very late, partly governed by the degree of immune-mediated component. The worst of the worst will experience severe problems by the time they are adolescents while the more resilient will not be affected until late in life. But, as I tell my clients, I believe that with the top four foods- wheat, dairy, soy, and corn- it is a matter of when they cause problems, not if. The “glue” will eventually affect everyone and every pet with its nutrient-blocking qualities.

 Suddenly, conditions such as hip dysplasia, elbow and shoulder problems, intervertebral disc syndrome, cruciate ligament ruptures, and even heart valve failure all have better explanations. All of these problems are caused by failing cartilage and connective tissue, both of which are structured similarly and made up of calcium and collagen. Collagen is the building block of most of your skeletal support structures. The principle component of collagen is vitamin C. Therefore, when it is understood that calcium is absorbed primarily by the duodenum while vitamin C and other vital vitamins and minerals are absorbed by the duodenum and jejunum, then it is easily seen that inadequate amounts of these in the diet or failure of their absorption will compromise the integrity of these structures- all of them.

 Once again, Pandora’s Box is opened and unleashed upon these poor breeds through one basic mechanism: malnutrition via malabsorption taking place in the small intestine.

I used to be concerned that the veterinary profession had somehow missed the incidence of celiac disease in breeds other than the Irish setter. But, now that I understand the effects of the “glue” on the absorptive ability of the intestinal villi, I believe this possible oversight to be much less important. I believe the same to be true for humans. The “glues” affect all that consume them. Certainly, the “worst of the worst”- the celiacs, casein intolerants, soy and corn intolerants- have the most to be concerned about. But, with these trouble foods, it is a matter of when they will create a problem, not if . Those who test negative for these food intolerances should not be lulled to sleep with a false sense of security. These fortunate souls will just be healthier longer. This is clearly one of the things that make us individuals, placing us on a spectrum of wellness that ranges from serious illness during the first year of life to a clean bill of health well into the twilight years.

 We must realize that a condition like osteoporosis is an end-stage result of chronic calcium deficiency and that there existed less identified but significant symptoms that preceded this dreaded outcome. Certainly we can affect the pace of these syndromes through supplementation and eating correctly in other regards. However, if we continue to consume the blocking agents, the “glues”, I am afraid that we will eventually lose the battle.

 If we don’t understand this, it is a matter of when… not if .

 FOOD in our health. Wow! What year is it again? How long have we been saying, “You are what you eat?” But, how many have understood this and grasped the full meaning of that statement and what has unfortunately become a worn out cliché’?

Many think in limited terms, I’m afraid, supposing that this expression means things like “eat your broccoli” or “don’t eat too much saturated fat“. Little do they know that the actual staples of their diet are harming them with every bite and setting the stage for most of the plagues that will befall them. When we add in the man-made chemicals, preservatives, colorings, and flavor enhancers, the self-induced nature of our suffering should become readily apparent.

A whopping 75% of the calories in the Standard American Diet (appropriately abbreviated the SAD) come from the number one and number two human, dog, and cat food allergens: cow’s milk and wheat. Why they are the top allergens and why soy and corn join them to round out the top four will be the main topics of this discussion. But as if this is not bad enough, 90% of prepared human foods have hydrogenated oils in them and 60% have MSG (monosodium glutamate), which we will be talking about very shortly. Throw in things like aspartame (a known neurotoxin and MSG’s evil twin), tons of sugar and salt, preservatives, chemicals, estrogens, pesticide residues, and more and you have a pretty good start on how we arrived at Helm’s Deep. When we see that the vast majority of pet foods are made with their main allergens, then we can understand why these little angels (elves) and dwarves are fighting right along side of us. Oh, and we can’t forget the horses. They are vitally involved in this battle.

In cow’s milk the culprit is casein , a very powerful glycoprotein, from which they make waterproof industrial adhesives . “What?” Yes, they make GLUE from casein. Who’s picture is on the bottle of a very popular brand of household glue, one that the kids could eat in elementary school if they had a craving for it (which we will also cover)? Yep, a well-known dairy company makes that glue and the cow is on the label. It is made from casein. And, it DOES stick to your (and your pet’s) gut, primarily that first stretch of the intestinal tract known as the duodenum, keeping this vital section of bowel from functioning optimally. Its adhesive properties are advertised in the form of a moustache in the ever-popular “Got glue?” ads. Stick out your tongue after drinking milk. Yuck! Is it really a stretch to think that it sticks to out intestinal tract? The thinking person is saying, “But the stomach breaks it down, doesn’t it?” The bad news is that, even with the tons of acid it produces…and the heartburn and chronic gastritis that follows…the glue still survives to reach the duodenum. (Only the fermentation process that takes place in the fore stomachs of the ruminant destroys this glue.)

Who knows this and how do we know? Most doctors both know and don’t understand this. (“Huh?”) It’s a conundrum to me, too. How can they know to tell you not to take certain medications with milk because it will block the absorption of that drug and not know that milk physically blocks other things at the same time? How can some pediatricians tell new moms not to give cow milk products until the baby is on an iron-rich diet and not see that this same milk blocks iron absorption in adults, contributing to the fact that iron-deficiency anemia is the number one nutritional deficiency in the world, including in these United States…the red-meat-consumption capital of the world. How can that be? Simply stated, we are not absorbing what we consume. And now we know EXACTLY why, don’t we? But, cow’s milk and casein are only the beginning. (Note: Why do I keep specifying cow’s milk? Here is the neat thing: goat milk is nearly devoid of casein, which is real reason why goat milk is considered the “universal foster milk”…and why the Greeks elevated the goat into the heavens…for the milk it gave. All mammals could be successfully raised on goat milk. BUT, feed those same infant mammals cow’s milk and watch how many come apart at the seams. The casein is the culprit, NOT the lactose. Goat’s milk has plenty of lactose. So much for that deception.)

Here is the important thing. The other “foods’ that coat (and subsequently damage) the intestinal villi…and the ONLY ones that do this along with casein …are gluten , soy , and corn . These are the big four or the “four horsemen of the apocalypse” as I now like to call them. And it is man and animals against casein, gluten, soy, and corn as the title implies. The strongest evidence of their potential harm is found in the fact that all of these food elements are used to make adhesives …powerful adhesives. Casein, gluten and soy are the strongest, stickiest, and most powerfully antigenic glycoproteins while corn is a slightly less powerful but nonetheless very significant player (especially the corn that we have recently created). They put cars together with the super-glues manufactured from soy protein. They make waterproof industrial adhesives from casein and gluten that are used for numerous purposes ranging from the glue on stamps and envelopes to putting metal together. But, the “best” they can do with corn glues is to put cardboard boxes together. So, we see why the FDA and veterinary lists of food allergens are what they are: in order, the ( primary ) food allergens are cow’s milk, wheat, soy, and corn. (We will discuss “secondary” allergens in a moment.) Soy could become number one…if that were possible. Fortunately, there are too many soy opponents who will keep this from happening.

The cow’s milk coating we had on the growth formulas was a HUGE problem that we are just now seeing the vital importance of. In a recent medical study, researchers in human medicine found that our children that ingested cow’s milk in the first five days of life had a staggering 40-50 times higher rate of asthma, type-1 diabetes, and juvenile-onset rheumatoid arthritis when compared to the general population. Oh, no! How could that be? You need to remember what is going on in the gut and immune system of the newborn during the first five days of life as well as understand the concept of “lectins”…antibody-sized glycoproteins derived from the big four…to really grasp the importance of this cataclysmic mistake. Much of this particular issue is outside of the time restraints of this presentation but I think you will find that this “fun fact” fits right into the grand scheme of things. We will discuss lectins a bit later, however.

Here is the key!!! As lecturers (and preachers) are fond of saying, “If you get one thing from what I say today then please get this.” The duodenum is “Pandora’s Box“. There. Got it? You can go home now. LOL. What? You don’t understand? I’ll say it more slowly. “The duodenum….is…..Pandora’s…….Box.” Of course you don’t understand…. yet! But you will and this little gimmick will help to keep it in your frontal lobe, I hope. Why do I call the duodenum “Pandora’s Box“? Because, once you “open” it ( damage it), you unleash the plagues…and potentially all of the plagues…that can befall man and animals. “Now wait a minute”, you might say. “I have been following this up to now but you are waaaay over the top now.” Hold on. This is going to be good…really good.

The sad and startling fact is that I have yet to meet a health professional (MD, DVM, or nurse) that has been able to tell me what the duodenum ABSORBS. In fact, I have had numerous casual conversations with members of all of these professions during which they looked me in the eye and boldly stated that the duodenum absorbs “nothing”. Then, once I remove the dagger from my heart (not throwing stones, of course, because before five years ago, I didn’t know either) , I go on to explain that the duodenum does nothing less than absorb the vast majority of our calcium, iron, iodine, B complex, vitamin C, zinc, boron, lithium, chromium, magnesium, lithium, manganese, blah, blah, and blah . In fact, it absorbs just about everything but our calories, proteins, fats, and fat-soluble vitamins (which is a lot of course). The amazing fact is that 95% of our vitamin D activity takes place in the proximal one-third of our duodenum, where the initial and majority of damage caused by the “big four” glue-foods take place.

Yes, the “glue foods” (as I like to refer to them) leave the stomach… glug, glug, glug …and coat the villi of the duodenum (and jejunum), especially the first one-third of the duodenum. Then, those glycoproteins from the gluten grains (wheat, barley, and rye), casein, soy, and corn induce an immune response in susceptible individuals. Certainly, not all people or pets have an immune response to these glues, but according to recent studies, the incidence is so much higher than once thought that anyone who understands this should have the same medical “revelation” that I have had…that we have found the “mother lode”.

When I was diagnosed as a celiac 5 years ago, it was considered a “rare disorder occurring in less than 1:5,000 people”. No wonder doctors (and veterinarians) had forgotten about it. But, in the first week of study about my new-found condition…the one that explained everything that was currently plaguing me and all that had been wrong with me since I could remember…I found that they were diagnosing people on the other side of the Atlantic at the rate of over 1:100. “Say what??? How could it be rare over here, when most of us came from those people…Anglo-Saxons, Italians, Scandinavians, French and Germans?” Yes, there was something amiss. So, I jumped into the study of celiac disease with both feet, discovering that casein, soy, and corn all did the same thing as gluten. I also found out the truth about hydrogenated oils, MSG, aspartame, sugar, the lactose myth, air pollution, and much, much more. (It was so profound that I started a parallel study in religion and prophecy. But that’s a whole ‘nother sermon. Smile .)

The fact is that the Mayo Clinic and Johns Hopkins University published their incidence studies last year and found celiac disease to afflict 1:122 Americans. Yes, that is the new “official” number. However, the unofficial number published by celiac authorities is 1:33. Whoa!

 But here’s the “bad news”. (Actually, you will come to see that this, again, is good news.) We are only talking about celiac disease here. And wheat is the number two food allergen. What is number one again? Cow’s milk (with casein). I wonder what the true incidence of casein-intolerance is? Is it more frequent than gluten intolerance? I would have to believe so. While wheat-containing foods (the targets of Dr. Atkins’ partial truth) make up nearly 25% of the calories of the SAD, cow milk products make up a whopping 40% of our overall caloric intake. Errrh!!! What about soy …the “third plague” as I like to call it.. Errrh, again!!! How about corn , the fourth horseman? Here’s a scary thought: What about a mix and match of the four…some or all of the “big four“? Think that happens? Of course it does. These guys can ride separately or they can form a gang. We all know a gang is harder to control, don’t we?

Now for the pathophysiology that you have been waiting for. The food allergies are just the indicators. During the time that the body is reacting to the “glue” from these foods, the IgE antibody…the allergy antibody…is formed to go out and warn us of the damage that is taking place in the duodenum. Otherwise, this is a stealth condition in most cases, with only one-fourth of celiacs and related food intolerants having gastrointestinal symptoms. Get that? That is very important. In fact, this is CRITICAL for all to understand, as it explains much and opens a door through which all truth-seekers must pass. (“There he goes, getting all melodramatic again.”)

“I’ll do it ’til I have problems. Then, I’ll quit.” (eg cigarette smoking, drugs, alcohol, or over-eating). The bad news is that by the time you have obvious problems with your lungs, liver, kidneys, heart, brain, immune system or duodenum , then you are waaaay down the wrong road. It is a consistent pattern that we can live on about 25% of our organ function…one half of one kidney, a fourth of our liver, multiple coronary arteries occluded, numerous neurons destroyed, etc. before ( BEFORE ) we even start having symptoms. That’s a good news/bad news thing isn’t it? As vets, we know that most of our conditions in the pet are “acute-on-chronic“…acute manifestations of chronic problems.

 Imagine now that over 1:30 humans have celiac disease or are afflicted with the other related food intolerances (casein, soy, and/or corn)…food induced villous atrophy of the duodenum. It can affect the jejunum as well. We know that this also occurs in the dog, with our old “extinct” friend the Irish setter being the glaring example. (I was absolutely ecstatic to hear that there was a pathologist in a major university in the northeast who has reopened the book on celiac disease.) Now, combine that fact with the consequences of the chronic malabsorption of calcium, iron, iodine, B complex, C, and numerous trace minerals, all of which are vital in the development and normal functioning of our bodies and immune systems. Do you have it in your mind yet? Let it sink in for a second. (Pause)

Which symptoms or clinical signs are likely to show up first? If you said gastrointestinal signs, you would be wrong (unfortunately). If you said signs associated with chronic calcium malabsorption or allergies you would be right. In some it is the former while in others the latter. The “worst of the worst”…those that have the earliest immune reaction to the glue foods…will have the IgE and IgG related symptoms first. These are your infants, human or pets, with congestion, itching, rashes, irritability, chronically sore throats, and ear problems. Some of them do have colic and diarrhea but these should not be required signs to make one suspicious of food problems. The “best of the worst” (and I rarely use the term the “best of the best” anymore) have the signs of calcium malabsorption first if they have any signs at all. Remember: the proximal one-third of the duodenum is greatly responsible for calcium metabolism and absorption. In the best-case scenario, these glue foods form a coating on these villi and keep them from performing optimally. (Here you go. Think of a beautiful coral reef with gorgeous sea anemones and multi-colored sponges. Got it? The “villi” of the anemones are swaying back and forth in the crystal clear water, absorbing small particles of food floating in the water. So serene, so perfect. NOW, imagine that same reef after the oil spill from the Exxon Valdez . Got that? How well do those anemones do when they are coated with oil? Some will survive but many, many will die. I think you have the picture.)

This is what the glycoproteins from gluten, casein, soy, and corn do. They coat the villi…at best…and “kill” the villi at worst, with the first and most severe damage taking place in the proximal third of the duodenum. No wonder I had flat feet, short legs, rib abnormalities and painful joint laxity…and bad teeth …as a child and later developed rotator cuff problems, bilateral inguinal hernias, and premature disc ruptures of my neck and back. I’ma classic celiac.

Shall I continue? I could give countless examples that would keep us into the wee hours of the morning. I think you are seeing the pattern here, right? The allergies are there to warn us that the damage is taking place in the gut. Again, the allergies are things “seen” to help us understand the things “unseen”. Watch for this pattern. It will come up again and again.

This is only the beginning, unfortunately and fortunately . (Please keep in the very front of your mind that the malabsorption syndrome leads to chronic deficiencies in so many vital nutrients. This is paramount in importance. Keep chanting, “Pandora’s Box, Pandora’s Box.“) We are still on the tip of the tip of the iceberg. And perhaps this is a good time to throw in the other analogy with which I was considering opening this dissertation. Try this one on for size:

Conventional medicine is steaming headlong into an enormous obstacle that is titanic in importance and yet has only a small piece of its mass protruding from the surface right now. The medical establishment (including both human and veterinary) has built a mighty vessel that many would deem unsinkable. “We have made such great gains in extending life” comes the announcement from the captain. “And one day, we will find the cures for cancer and the diseases that plague us all.” And the passengers all say “Hooray!!! It will be clear sailing from there!” The applause dies down and the captain exclaims, “And we are working on better ways to make these necessary drugs more available, more well-known by the public, and more affordable to you. Very soon, many of these drugs will be available over-the-counter and you will no longer need to even consult with your physician about them. Simply choose what is right for you by watching your television and then going to your local drugstore, supermarket, or gas station food mart to pick them up. You will be wise enough to choose for yourself.” Again, the crowd roars with approval.

But, there is something looming in the waters, just off the port bow. Some call it an iceberg. Others call it a “rock”. I call it the Truth . This treatise so far has mapped out the tip of the tip of this iceberg. With the binoculars you now have, you can see it. Do you see it??? If your eyes are good enough, you can see much of what is below the surface, too. The water is a lot clearer out in the ocean than you may think. And this “unsinkable” vessel that man has created is heading straight for it. Why? They are not looking for it. Many are happy, quite content with the cruise they are on. Others don’t really know any other way to behave on a cruise like this. Others are desperately trying to keep those who would worry about icebergs distracted so that they don’t spoil the cruise for the others. Ignorance and greed are at the controls…our two biggest nemeses… with contentment being a first mate.

But, it is this same technology that does not seem to understand that taking an NSAID for a fever caused by a viral infection is not a wise thing to do. It is the same captain’s mates that don’t see that Helicobacter pylori…the opportunistic bacteria that causes deep stomach ulcers… hates an acid stomach and that heartburn is designed partly to control his growth. If they don’t know that, then they certainly can’t see how this beast that they have been feeding with antacids and problem foods leaves the stomach when the individual’s immune system takes a nose dive (after a lifetime of malabsorbing nutrients vital to its health) and takes up residence in a cholesterol plaque (that is safe-guarding a weakened artery) and causes it to break off, inducing a stroke or a myocardial infarction. How can they see that? They have their eyes on the moon and the stars. (And yet, a study done by a group of cardiologists found that a shocking 85% of atherosclerotic plaques that were cultured for H. pylori were positive for this critter. Think about that for a second. Sinking in?)

 They develop so many of the conditions that take human life, including a higher incidence of cancer, but dogs don’t suffer from this deadly disease process. Why is that? Simply put, they don’t get “enough” hydrogenated oils in their diet. I believe down to my socks that trans fats are the single-most important factor in the development of atherosclerosis…the “solvents” that allow things into the walls of the arteries of those that consume them and set the stage for the inflammatory process that follows.

 (Please read Hydrogenated Oils-The Silent Killers , by David Dewey on the Internet. Whoa! You will clearly see how and why the first recorded myocardial infarction took place only ten years after hydrogenated oils hit the shelves in the form of margarine. You will also see how and why another plague…type 2 diabetes…”adult-onset“ diabetes…followed ten years after that.

 The “four horsemen” fit right into the clinical picture here by inducing at least two of the three factors- causing immune suppression and inciting chronic tissue inflammation and damage. The immunosuppressive effects of the big four should be easily imagined. Back to the coral reef covered with oil. How can those villi that are coated with the problem glycoproteins manage to absorb optimal levels of B complex, vitamin C, and other nutrients critical to the health of the immune system? How can they do it when they are leveled by the immune response to the glue foods in true celiac disease or the related conditions of true casein, soy, or corn intolerance? This should be a no-brainer… and it is …. literally. The brain suffers tremendously from the lack of these nutrients along with a concurrent deficiency in calcium, zinc, iron, iodine, and the pandemic omega three fatty acid deficiencies that exist in humans and pets.

 The “big four” foods fit right in here because the gluten grains, dairy, and soy are loaded with estrogens. Dairy is a huge factor here as it also provides cholesterol precursors to the formation of these hormones. Seeing a pattern here? Yes, the foods that are bad for us are so in a numbe r of ways. So, we should not be surprised to see that Asians have a 15 times lower rate of breast cancer and a 5 times lower rate of prostate cancer…on their native diets. It is NOT because they eat soy. The truth is that they eat very little soy. But they do NOT eat dairy, wheat, or corn in their original diets. Just go to any authentic Japanese or Chinese restaurant and look for the cheese, bread, or corn chips.

Which brings us to “lectins”, something I mentioned a while back. Lectin is the term that has been given to the antibody-sized glycoprotein that is derived from the consumption of foods that are part carbohydrate and part protein (thus the term glyco-protein). Once again, the big four foods are glycoproteins by structure. Our antibodies are also glycoproteins, a protein core with a sticky carbohydrate outer covering to facilitate adherence to foreign proteins such a viruses, bacteria, and the like. In fact, viruses have glycoprotein receptors on them. Normally, our antibodies attach to these sites. Hmmm…I wonder if dietary lectins ever do? Could one plausible explanation for food-induced immune-mediated disease episodes be that the chronic latent viruses in situ in our tissue become coated with dietary glycoproteins rather than our antibodies and that when we develop IgE, IgG, and other antibodies to these foods that our immune system starts to react to these “food-coated” viruses in the host tissue and attack that tissue just as it would if it were a viral infection coated with our own antibodies? Could that be how food lectins such as those from wheat, dairy, soy, or corn auto-agglutinate red blood cells. Maybe it is just the glycoprotein itself that does it in most cases but it sure would help to explain why some “autoimmune diseases” are triggered by foods while others follow viral infections, either naturally acquired or through vaccination . It would also help to explain why avoidance of the trouble foods could greatly reduce the incidence of recurrence of these attacks. (For a well-written discussion on lectins, please look up The Lectin Report on the Internet. It goes into great detail about how these tiny glycoproteins “unlock” the cell and allow things to enter it, inciting inflammation and causing cell death. It’s all about the same guys. The four horsemen ride again.)

 The fantastic news is that sooooo much starts going right once the big four are avoided completely and for a long enough time. By avoiding the casein, gluten, soy, and corn, the gut starts to heal and the malabsorption syndrome begins to reverse. How long does it take for the intestine to heal once the offending foods are withdrawn? Well, according to the celiac literature, it takes anywhere from 6 months to 2 years for the duodenum to return to normal. Does that make sense? Not to me, unless you consider the fact that gluten is not the only thing doing the harm to those duodenal villi. This was my first quest, to get on celiac forums and make sure they knew the truth about casein, soy, and corn. I hated reading about celiacs that had struggled so valiantly to be gluten-free only to find that they were shooting themselves in the foot big time by the continued consumption of the other three culprits. Statistically, celiacs have a 50% chance of also being casein intolerant. I have to believe that it is much more common than that. But soy and corn are looming larger and larger as we fall for the myth that soy is a health food, we turn to vegetarianism for various reasons, and we continue to genetically modify corn to death.

Assuming that we do enough right, the gut does heal and probably much more quickly than we currently believe. After all, it is one of the fastest healing tissues in the body. Once healed, it starts to take in all of the calcium, iron, iodine, B complex, vitamin C, and trace minerals that it has been starving for over the past years, often from the moment the individual started consuming the big four. The thyroid becomes healthy, the iron deficiency resolves, enzyme systems start operating at peak efficiency, tissue repairs, and the immune system gets back to normal. And that last item is critical . That’s when many of the long-term symptoms finally resolve…the allergies, GI signs, skin problems, and in the best case scenario, the immune-mediated diseases. I would love to think that the risk of cancer then plummets, as well. What couldn’t our immune system accomplish if it were in optimal condition? I can no longer put limitations of what our body is capable of doing in the way of healing or prevention when I think about that last statement. However, I know that our environment…with its staggering levels of serious pollution…is a HUGE limiting factor. I would love to dive into that topic but time constraints do prevent that.

The really cool thing is that some “completely unexpected” things can happen when individuals go GFCFSFCF (gluten-free, casein-free, soy-free, corn-free). In retrospect, they were “unexpected” only because we had not fully grasped the impact of what we had learned. The most notable…the most amazing…the coolest of the cool…the “hook” as I now call it…was the response of epileptics to this elimination diet. I find it just so utterly fascinating that something we stumble upon can wind up be the glaring example of everything we know… AND end up leading us into realms that we could only dream about in the past. Epilepsy is just that condition.

Man, I could talk about epilepsy for the full two hours- how it all comes about and what the study of this condition has done to my knowledge base . Thankfully, I have chronicled the entire journey on my Website (www.dogtorj.com ) , starting with how I read the captivating fact that celiac children with epilepsy who went gluten-free often had major reductions in…if not total cessation of…their seizures. “Wow. I wonder why that happens?” I asked myself. “Epilepsy is considered idiopathic in veterinary medicine. There has to be something about wheat that leads to seizures.” Elementary thinking, I know. But, this was novel stuff to me. How about you?

It did not take long at all to find that MSG (monosodium glutamate) could trigger seizures and that wheat gluten was an incredible 25% glutamic acid by weight. “Eureka! Is it that simple? I then found that soy had even more glutamate, almost twice as much as wheat. “Oh, oh.” Casein is 20% glutamic acid by structure. Yep, three of the four horsemen are packing glutamate in their saddlebags. Do the food sources of these neurostimulating… potentially neuro toxic …non-essential amino acids (glutamate and aspartate), really do the same thing to our brain that the “crack cocaine” versions (MSG and aspartame, respectively) do?” I assumed so and started putting my epileptic canine patients on gluten-free diets and, son-of-a-gun, they became vastly improved. Some stopped having seizures completely within 24 hours of the diet change and never seized again. We were onto something… and it was big …really big.

As the significance of these findings sunk in, I threw myself into the study of neurological, psychiatric, and other “idiopathic” neurodegenerative conditions that affect us all. The “excitotoxins” ( MSG and aspartame), as Dr. Russell Blaylock termed them, were well-known culprits and played roles in epilepsy, ADHD, bipolar disease, and more. It wasn’t until later that I would finally start reading about their involvement in the other “big 4”: MS, ALS, Alzheimer’s and Parkinson’s. But still, no one was talking about the FOOD sources of these non-essential amino acids. But it was so simple, and a little something called “insomnia” illustrated the point I was trying to make. These neuroactive amino acids were clearly responsible for waking people up like a shot at 1-2 AM, 5-6 hours after eating dinner and dessert and I was a living example. And that was the exact time interval I was finding between meals and seizures in my un-medicated dogs. Once I published my work on the Web and contacted over 500 breeders in the process (oh, how I love the passion of breeders), the testimonies to these finding were flowing in on a regular basis. And, the pieces to this puzzle started fitting together…phenomenally well.

And here is where it all comes together. I had written a totally different summary for the end of this discussion, but upon proofreading the pages, I realized that the discussion of epilepsy…the condition that grabbed my attention and pulled me into this epic battle at Helm’s Deep…would serve that purpose. It would illustrate all of the principles that I “preach” every day in the exam room and will attempt to enlighten people with (hopefully not bore to death) in lectures like this for the rest of my days.

Principle number one: The foods that are bad for us are bad in numerous ways. The “four horsemen”…gluten (from the grains wheat, barley, rye), casein, soy, and corn terrorize us in more ways than simply inducing villous atrophy, which results in the chronic malabsorption of the essential nutrients that we have covered. These foods provide staggering levels of glutamate (and aspartate), estrogens, allergens, and lectins, and when prepared for consumption, act as carriers of many of man’s worst creations in the form of GMO’s, hormones, and chemical additives. So these foods damage our gut, cause malnutrition of our entire body, and provide many of the ingredients necessary to generate symptoms including pain, sleeplessness, high blood pressure, behavioral disturbances, and seizures .

Applying this to epilepsy, the brain suffers from the malnutrition, the immune system going down, and the rise of chronic latent viruses The war begins. Add to that the vaccination with modified live virus vaccines made with viruses that love the central nervous system. These viruses naturally take up residence in the glial cells of the brain, those cells that control the level of the normal neurotransmitter…our friend glutamate …at the synapse. We have seen vaccine-induced disease in the past, right? How hard is it to believe that this is happening “ sub -clinically“? These top allergy-producing foods are also stimulating histamine production, the release of which causes the blood brain barrier to become more permeable to glutamate, a normal occurrence that serves to counteract the depressing effects of histamine. These same foods contain estrogens , both naturally occurring and those from pesticide residues, which are neurostimulating, irritating, and immunosuppressive. PMS anyone? How about catamenial seizures? I hear about them all of the time. The malnutrition that we have discussed then starts to compromise enzyme systems in the liver, kidneys, and elsewhere in the body, some of which are responsible for controlling the blood levels of the evil twins, glutamate and aspartate. No wonder some of us have seizures. The way I see things now, it’s a bigger wonder that more of us don’t have epilepsy.

Are you seeing “Pandora’s Box” opening yet? Have you grasped what these foods- the damage they do and the ingredients they contain- are capable of? Thank Goodness our body knows what to do with all of this mess we put it through, eh? And it does.

Therefore, principle number two: Our body never makes mistakes…ever. Only we make bad choices about what we do to this vessel of ours. “What about birth defects?” is always the first challenge. Certainly, this degenerative process sometimes begins prenatally, leading to premature births and birth defects, but we are ultimately responsible for these occurrences. The more you learn about this topic (and study celiac disease as a model), the less you will simply write off to “genetics” or Providence.

Fevers, heartburn, sore throats, nasal congestion, bronchoconstriction, diarrhea, hives, headaches, and even “autoimmune” attacks have a purpose. Some clinical signs are warning signs that we have made a mistake while others are therapeutic measures on our body’s part. Others are both. “But autoimmune disorders?”, you might question. Yes, I believe down to my socks that viruses are vitally involved in most (if not all) immune-mediated diseases. I believe that the immune-mediated diseases are our immune system’s valiant attempt to wipe out these viruses before they have the opportunity to do what they really “want” to do…cause cancer . This would help to explain why people with chronic active hepatitis have such a high incidence of liver cancer. But it might also help to explain why the same breeds of dogs that develop panosteitis…the ones with all of the allergies and other juvenile bone diseases…are the guys that go on to develop bone cancer at age six and a half. So, is eosinophilic panosteitis our body’s attempt to rid the bone of viruses that might later go on to cause cancer? What are eosinophils involved in other than allergic reactions?

“But get back to seizures. I can’t wait to hear how a seizure is a good thing“, the skeptics are saying. Yes, I am convinced that even seizures serve a vital purpose, that being to burn up the excessive glutamate in the brain. As you may know, no matter what the cause of our bodily death may be, the brain dies as a result of the “glutamate cascade”…the sudden rise of glutamate in the brain resulting from the dying glial cells and increased permeability of the blood brain barrier. Glutamate is potentially…and eventually…neuro lethal . How hard is it to believe that seizures are designed to keep the death of vital neurons from happening? The sufferers of ALS (Lou Gehrig’s Disease) sure wish a peripheral neuron could have a seizure. But because they can’t, the neurons eventually die as a result of the excess glutamate in the synapse. But guess what. ALS sufferers have also reported benefits from what I now call “The GARD“…. the glutamate-aspartate restricted diet. So have people with ADHD, chronic pain, insomnia, MS, and other conditions that have the “excitotoxins” as part of their pathophysiology. This is all on my site.

Seizures may even serve to limit viral infections, if through no other mode of action other than to encourage a rise in body temperature, something that viruses hate. We know that viral infections of the central nervous system are usually accompanied by high fever, right? Remember: That’s a good thing. (I wonder how many people who died of West Nile Virus might have survived if we didn’t treat them so aggressively? Its a parallel to that cancer thing we talked about earlier.)

So, do you see why I got so excited about the role epilepsy would play in bringing people into the fold? It has all of the elements we have discussed…all of the necessary cast, plot, and scenery to make a great and epic tale of how the four horsemen road into town and stole our health. But we really did it to ourselves, didn’t we? We made these bad choices. The fact is man created the wheat we now eat in about 400 AD, introducing lethal quantities of gluten into our diet. A millennium later, we changed milk sources from goats to cows, adding casein to the mix. Now, five hundred years later, we want to start eating soy…“the third plague”…something that has been previously relegated to the lowly positions of a nitrogen-fixing, rotational crop and a mere condiment on the table of our Oriental restaurants. Did we really just get smart enough to see the health benefits of consuming the soybeans themselves? Do we really think that loading our bodies up with plant estrogens, goitrogens, anti-nutrients, villous atrophy inducing “glues“, and staggering levels of the non-essential, epileptogenic amino acid glutamate is going to improve our health. How many trips to Mars are we gonna take, anyway?

We do reap what we sow. Through the eyes of food intolerance, medicine becomes so simple that even* the layperson can understand it. (* I say “even” because I know a growing number of lay people who understand these things much more than the doctors who look down their noses at the “untrained“.) Isn’t that the way it should be? Shouldn’t we all be able to comprehend our medical lives? It is, after all, one of the most important aspects of our existence, isn’t it?

The way I look at it now, our medical lives are divided into three phases: the acquisition of viruses, the progressive malfunction of our body and immune system, and the failure of our immune system. I think you now have a very good idea why that occurs. In a word, malnutrition . Symptomatically, it usually also breaks down into three phases: allergies, immune-mediated diseases, and cancer. We see this so clearly in certain breeds of dogs but I have also heard this sort of history from many, many from people I have interviewed about their own health. Hopefully how and why these three phases occur is much clearer now. The allergies… phase one .. are the warning sig ns that you are making mistakes. The immune system is throwing warning signs at us while closing the doors to further invasion.

 Better put, what doesn’t happen at that age: tons of immune-mediated diseases, cruciate ruptures, spinal disorders, heart murmurs, worsening allergies, numerous benign skin tumors, and more. It’s a crisis period, isn’t it? Just like 40-50 years of age is in the person. If these conditions are all “genetic”, why do they wait so long to show up? Hmmm…great question. Something is waiting, right? What??? Can we think of anything that we have in our bodies that might be “waiting”? I can. They’re called viruses . We have been acquiring them our entire lives. Our parents even gave some to us. “What?“ Can’t viruses be transmitted vertically? How about genetically? Others we acquired “naturally” during our lifetime and still others we acquired through vaccination . (Most of our pets and us are too unhealthy to take on any more modified live vaccines, aren’t we?) And as I have mentioned , we invited many in to stay by killing the fever that was designed to limit the infection. We have become walking virus hotels…”mobile homes” for these guys, if you will. The startling fact is that we are riddled with ’em. And they are waiting for their chance. They are the ultimate opportunist…the consummate terrorist. Sure, there are others: bacteria, mycoplasms, fungi, and more. But the virus is the guy who incorporates his genetic material into our cells and then bosses them around. He’s the guy who our immune system hates enough to risk killing our own tissue to root him out. He’s the guy that can go anywhere in our body and do anything he wants ONCE we get to that point of immune suppression that we are destined to reach once we have done enough wrong to this body of ours. In my mind, he wasn’t designed to be. Viruses are ubiquitous in nature and critical to its development, variety, and adaptation. So why did they turn on us? “Shoot…look at the time. We’ll have to go down that rabbit hole after this presentation.” I think you can figure it out, anyway.

 Yes, we DO have our health destiny more in our own hands than we ever believed. Yes, we DO reap what we sow. We just didn’t realize that we were sowing such bad seed all of these years did we? We have had glimpses of our wrongdoing and our conscience has told us not to overindulge and to try to eat properly. That’s just common sense, right? But whodathunk that the staples of our diet were killing us? Who would believe that cow’s milk, wheat, and the “newest health food”… soy (errrrrh)…were plagues on mankind, brought on by our own doing? And who would believe that the “simple” elimination of the big four would lead to the vast improvements in our health that I have personally experienced. (I cannot overstate the phenomenal changes that have taken place in my body over the past 5 years)

Dogtor J.

(Excerpt)

http://dogtorj.tripod.com/id23.html