The mechanism of dead-in-bed syndrome and other sudden unexplained nocturnal deaths

Abstract The mechanism of dead-in-bed syndrome (DBS), a rare but devastating condition that mainly affects young type 1 diabetes patients, remains mysterious. A new theory is proposed to explain this syndrome. This theory suggests that repeated episodes of hypoglycaemia-induced adaptation in orexin-A neurons cause (i) defective awakening and (ii) hypotonia of upper airway muscles during… Read More The mechanism of dead-in-bed syndrome and other sudden unexplained nocturnal deaths

High glucose levels could impair ferroelectricity in body’s connective tissues

Michelle Ma News and Information High sugar levels in the body come at a cost to health. New research suggests that more sugar in the body could damage the elastic proteins that help us breathe and pump blood. The findings could have health implications for diabetics, who have high blood-glucose levels. Researchers at the University… Read More High glucose levels could impair ferroelectricity in body’s connective tissues

Hemoglobinopathies May Distort HbA1C

Natasha Patel, PharmD Candidate, LECOM College of Pharmacy Measuring glycated hemoglobin (HbA1c) gives us a patient’s long term average blood glucose levels.1 Since HbA1c measures the percentage of patients’ glycosolated hemoglobin, patients who possess variants of hemoglobin can exhibit false readings. Such variants, called hemoglobinopathies, can include inherited hemoglobin variants, elevated fetal hemoglobin, and hemoglobin… Read More Hemoglobinopathies May Distort HbA1C