I certainly think there are strong correlations between IBS and thyroid and the common ties are lectins, nutrient malabsorption, and the rise of embedded viruses. I believe that PLE is actually a chronic anti-viral battle in which the food lectins (along with some chemical sensitivities) have caused the chronic, latent enteric viruses to adapt into something the immune system no longer tolerates and is called in to keep them under control.
The removal of some preservatives, etc. can cause partial remission of signs but the key to the long-term treatment is the elimination diet (especially the removal of all gluten, casein, soy and corn). This allows things to get back to normal. We all know the role corticosteroids play in short-term and long-term management, usually having transient success as treatments just like in their use in other immune-mediated diseases, which helps to prove the role of food proteins (lectins) in the pathogenesis. The initial damage done to (reactions incited in) the cells by lectins is independent of the immune system. The immune response follows this initial biochemical damage, which explains why symptoms abate but the condition persists.
Why the boring review? Because the same thing is happening in the thyroids, right? And the nature of the virus in the thyroid of the individual determines the form of thyroid illness that follows the lectin insult.
In the human, it can be either Hashimoto’s or Graves that occurs (in keeping with the interesting fact that humans can get viruses from animals but not the other way around) and thyroid cancer is common. So, it is easy to assume from this that viruses ARE involved in thyroid illness, where the hypothyroidism is purely from iodine malabsorption.
Why does the iodine malabsorption take place again? Due to villous atrophy of the duodenum where the iodine is normally absorbed. This is extremely common in celiacs and is part of the syndrome induced by the lectins of gluten. Do these same lectins head off to the thyroid and induce hypothyroidism in sensitized individuals? With celiacs having a 50 times higher rate of hypothyroidism, I’d have to say yes. Are all celiacs hypothyroid? No, not all have the virus or ever experience the right combination of factors that leads to their expression. But between the malabsorption of iodine (being blocked by the “big 4″…gluten, casein ,soy, and corn) and the true immune thyroiditis, staggering numbers of us have low thyroid levels.
The food allergies are the outward manifestation of the internal damage to the gut, with IgE being formed at the time the lectins damage the villi. IgG is also formed to these food glycoproteins and later becomes involved in the more serious immune-mediated diseases. The bad news is that not all individuals form IgE to the offending foods. Not all celiacs are allergic to wheat. This is bad news.
Type A blood in people, the most dairy intolerant. Alpha S-1 casein loves to stick red cells together just like (Borden’s) Elmer’s glue (from casein) holds things together.
MSG and Hypothyroidism
Many MSG sufferers have been diagnosed with thyroid conditions. The most prevalent being hypothyroidism. Many are taking the prescription drug Synthroid.
What does this have to do with MSG?
MSG can damage the hypothalamus as proven by Olney in experiments so groundbreaking that American food companies took MSG out of baby food after the results of Olney’s study were released to the public.
What does this have to do with the thyroid?
The hypothalamus is the part of the brain that monitors the body. It is the body’s “sensor”. Hormones and temperatures are measured and based on this info, the hypothalamus sends out signals to the “master gland” the pituitary located just underneath it, and behind the eyes. The pituitary gland then sends out chemical signals that direct the entire endocrine system. This includes the thyroid, as well as all the other endocrine glands in the body. Damage to the hypothalamus affects the entire body.
Why is this important?
The thyroid gland is necessary for life. It directs the body’s metabolism.
Could the overuse of MSG have caused the hypothyroid condition of unsuspecting people? Is that what makes many of those hypothyroid patients, also MSG sensitive?