Role of Hepatic Glycogen Breakdown in Defective Counterregulation of Hypoglycemia in Intensively Treated Type 1 Diabetes

FIG. 1. Physiological defenses against hypoglycemia. It is important to note that the decreased insulin secretion and increased glucagon release are lost and the increase in epinephrine is often attenuated in type 1 and advanced type 2 diabetes. AA, Amino acid.

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