How to Estimate an Insulin-to-Carbohydrate Ratio

Posted on May 20, 2007

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How to Estimate an Insulin-to-Carbohydrate Ratio for 50 kg patient with a total daily dose 1 unit/kg/day.

1. Total daily dose of insulin for such patient will be 50 unit/day (1 unit/kg/day for 50 kg patient)

2. Insulin-to-Carbohydrate Ratio

500 Rule = 500/(total daily dose)

500/50 =10 (therefore give 1 unit per every 10 grams carbohydrate eaten)

How to estimate correction factor for 50 kg patient with a total daily dose 1 unit/kg/day.

1500 Rule = 1500/(total daily dose)

1500 =30 (therefore 1 unit of short acting insulin given will decrease blood
50 glucose by 30 mg/dl )

3. Target blood glucose– we use 150 mg/dl in the beginning while training and later 120 mg/dl after patient is comfortable with the insulin schedule.
Example: In case of blood glucose 300 mg/dl and target blood glucose 150 mg/dl:
Correction factor = 300 -150/30 = 5 unit of short acting insulin ( therefore 5 unit of short acting insulin will decrease blood glucose to 150 mg/dl).